Bisphosphonate drug holidays

Evaluation of fracture risk and potential drug holidays for postmenopausal women on long-term bisphosphonate therapy

STUDY OBJECTIVE To describe characteristics of postmenopausal women on long-term bisphosphonate therapy who fall into one of four fracture risk categories (low, mild, moderate, high), and to determine the prevalence of women eligible for a drug holiday. DESIGN Retrospective electronic health record review. SETTING Eight primary care clinics within a university-based health care system. PA...

Use of drug holidays in women taking bisphosphonates.

Bisphosphonates are the cornerstone of treatment for osteoporosis. These agents are generally safe and well-tolerated, but concerns have emerged about adverse effects related to long-term use, namely osteonecrosis of the jaw and atypical femur fractures. For most patients at moderate or high risk of fracture, the benefits of treatment far outweigh these serious but rare risks. Bisphosphonates a...

Sunday Holidays

. Sir, Will you please find .1 little space for my proposal 111 your valuable paper and oblige. It is rather curious that the medical department should have no holiday unlike other departments, and it is sometimes a matter which causes great inconvenience to its employs. Some years back the work of the Indian dispensaries was light as most of the people were used to the eastern methods of treat...

Happy Holidays

Holidays in the sun.

If you are reading this editorial in the week of publication, chances are that you do not work in one of the countries bordering the Mediterranean. If you are in Scandinavia, this is probably your first opportunity even to read my editorial from July. Most of Europe now takes a full four or five weeks of vacation, usually corresponding to the calendar month of July in the north or August in the...